UCLH Cancer Collaborative is partnering with Amgen to map out and measure the most efficient out-of-hospital administration of denosumab, also known as Xgeva, a targeted therapy used for the treatment of secondary breast cancer in the bone. Additionally, Quintiles IMS will be providing technological expertise to the project.

Outputs from one to one stakeholder interviews, workshops and patient surveys, will feed into a simulation modelling tool that allows different delivery scenarios, whether at hospital, in primary care, in the community or at home to be to be tested for financial and patient experience impact..

An options appraisal document and user guide will accompany the model in a toolkit available to all NHS Trusts and clinical commissioning groups. UCLH may further collaborate with Amgen to tailor a business case for a permanent out of hospital denosumab service within the Trust.

The project toolkit will be shared via this website when available.

For more information please contact Pinkie Chambers or Simon Evans.